2004 publications supported by the Fungal Research Trust directly or indirectly

Birch M, Denning DW, Robson GD. A comparison of extracellular phospholipase activities in clinical and environmental isolates of Aspergillus isolates. Medical Mycology 2004;42:81-86.

Hope WW, Denning DW. Invasive aspergillosis: the current and future challenges in diagnosis and therapy. Clin Microbiol Infect 2004;10:2-4.

Pain A, Woodward J, Quail MA, Anderson MJ, Clark R, Collins M, Fosker N, Fraser A, Harris D, Larke N, Murphy L, Humphray S, O’Neil S, Pertea M, Price C, Rabbinowitsch E, Rajandream MA, Salzberg S, Saunders D, Seeger K, Sharp S, Warren T, Denning DW, Barrell B, Hall N. An insight into the genome of the most abundant opportunist human pathogen: analysis of 922 kb fragment of chromosome VIII of Aspergillus fumigatus. Fung Genet Biol 2004;41:443-53.

Warn PA, Sharp A, Guinea J, Denning DW. Effect of hypoxic conditions on in vitro susceptibility testing of amphotericin B, itraconazole and micafungin against Aspergillus and Candida. J Antimicrob Chemother 2004;53:743-9.

Hope WW, Padwell A, Guiver M, Denning DW. Invasive pulmonary aspergillosis with spontaneous resolution and the diagnostic utility of PCR from tissue specimens. J Infection 2004;49:136-40.

Kamran M, Calcagno AM, Findon H, Bignell E, Jones MD, Warn PA, Hopkins P, Denning DW, Butler G, Rogers TR, Mühlschlegel F, Haynes K. Inactivation of the ACE2 transcription factor gene in the fungal pathogen Candida glabrata results in hypervirulence. Eucaryotic Cell 2004;3:546-552.

Calcagno AM, Bignell E, Rogers TR, Canedo M, Muhlschlegel FA, Haynes K. Candida glabrata Ste20 is involved in maintaining cell wall integrity and adaptation to hypertonic stress, and is required for wild-type levels of virulence. Yeast. 2004 May;21(7):557-68.

Hope WW, Denning DW. Optimising antifungal therapy for individual patients (Editorial). Intern Med J 2004;34:147-9.

Hope WW, Denning DW. Antifungal therapy. MIMS Advances 2004 July: 8-11.

Hwan Do J, Anderson MJ, Denning DW, Bornberg-Bauer E. Inference of Aspergillus fumigatus pathways by computational genome analysis; Tricarboxylic acid cycle (TCA) and glyoxylate shunt. J Microbial Biotechnol 2004:14:74-80.

Boyd AE, Modi S, Howard S, Moore CB, Keevil BG, Denning DW. Adverse reactions to high concentrations of voriconazole. Clin Infect Dis 2004;39:1241-4.

Keevil B, Newman, Lockhart S, Moore CB, Howard S, Denning DW. Validation of an assay for voriconazole in serum samples using liquid chromatography- tandem mass spectrometry. Ther Drug Monit 2004;26:650-657.

Zaspel U, Denning DW, Lemke AJ, Greene R, Schurmann D, Maschmeyer G, Ruhnke M, Herbrecht R, Ribaud P, Lortholary O, Zonderland H, Rabe KF, Rottgen R, Bittner R, Neumann K, Oestmann JW. Diagnosis of IPA in HIV: Role of chest-X-ray and radiologist. Eur Radiol 2004;14:2030-7.

Hope WW, Tabernero L, Denning DW, Anderson MJ. Insights into the molecular mechanisms of primary resistance to 5-fluorocytosine (5FC) in Candida albicans. Antimicrob Ag Chemother 2004; 48:4377-86.